Score alcoholic hepatitis severity with the Maddrey discriminant function from prothrombin time and bilirubin.
Result
How to use this tool
Use seconds from the coagulation report.
Use the laboratory control prothrombin time in seconds.
Use mg/dL.
32 or above is severe alcoholic hepatitis by this score.
Formula & worked example
Patient prothrombin time 20 seconds against a control of 12 seconds with bilirubin 10 mg/dL gives 4.6 x 8 + 10 = 46.8, severe alcoholic hepatitis.
Limitations — read this before you rely on it
Severity score only. Treatment decisions also need infection exclusion, MELD, Lille response and clinical judgement. This tool is for education only and is not medical advice. Talk to a clinician about any result that worries you, and never change treatment because of a calculator result.
Frequently asked questions
A severity score for alcoholic hepatitis combining prothrombin time prolongation and bilirubin.
32 or above defines severe alcoholic hepatitis.
The coefficient weights prothrombin prolongation relative to bilirubin in the original discriminant analysis.
Not alone. Steroid decisions need infection screening, contraindications and other prognostic scores.
The difference is negative and lowers the score; check the values, as this is unusual.