Hydroxychloroquine Dose Calculator

Work out the weight-based maximum daily hydroxychloroquine dose for lupus and rheumatoid arthritis, capped at 400 mg.

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Result

Daily maximum
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Tablets
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Calculation
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How to use this tool

1
Enter body weight

Use actual body weight in kg, or pounds with the unit switch.

2
Choose the use

The rheumatology cap applies to lupus and rheumatoid arthritis.

3
Read the maximum

The prescriber rounds to a practical tablet dose.

4
Do not self-adjust

Eye screening and prescriber review govern long-term use.

Formula & worked example

Maximum daily dose = minimum of (5 mg/kg x actual body weight in kg, 400 mg). Tablets = maximum dose / 200 mg.

At 60 kg the rheumatology maximum is 5 x 60 = 300 mg per day (1.5 x 200 mg tablets, rounded by the prescriber). At 80 kg the uncapped 400 mg is reached exactly, and heavier weights stay capped at 400 mg.

Limitations — read this before you rely on it

Published/labelled maximum only; actual dosing is clinician-determined and malaria regimens differ. This tool is for education only and is not medical advice. Talk to a clinician about any result that worries you, and never change treatment because of a calculator result.

Frequently asked questions

For lupus and rheumatoid arthritis, guidance caps hydroxychloroquine at 5 mg/kg of actual body weight per day, up to 400 mg daily.

Higher long-term doses raise the risk of retinal damage, so the cap and regular eye screening protect vision.

Malaria treatment and prophylaxis use different prescriber regimens; this tool’s daily maximum is the rheumatology cap, not a malaria schedule.

200 mg tablets are the usual strength; the prescriber rounds the calculated dose to a practical tablet regimen.

Anyone with eye disease, severe kidney or liver disease, or interacting medicines needs prescriber review first.